A 24-year-old woman presents with a non-itchy rash and no improvement from topical cream. What is the most appropriate initial treatment?

The most appropriate initial treatment for a 24-year-old woman presenting with a non-itchy rash and no improvement from topical cream is narrow-band UVB phototherapy. This approach is often utilized for skin conditions such as psoriasis or other inflammatory dermatoses that may not respond to topical treatments. Narrow-band UVB therapy is effective in reducing inflammation and promoting healing in various dermatological conditions by exposing the skin to ultraviolet light, which can modify the immune response and improve skin health.

In cases where topical treatments fail, particularly with non-itchy rashes that may indicate a chronic inflammatory skin disease, phototherapy can provide significant relief and improvement. The use of this therapeutic option is supported by evidence highlighting its efficacy in managing certain dermatological disorders.