Which drug is most likely to cause a hand tremor in a patient who had a successful renal transplant?

Tacrolimus is the drug most likely to cause a hand tremor in a patient who has undergone a successful renal transplant due to its mechanism of action and side effect profile. As an immunosuppressant, tacrolimus is critical in preventing organ rejection post-transplant, but it is known for its potential neurological side effects, one of which includes tremors.

The mechanism behind this tremor is thought to be related to its effects on the central nervous system, possibly due to alterations in neurotransmitter systems or effects on muscle activity. Hand tremors are observed in a significant number of patients on tacrolimus therapy, and this side effect can be dose-dependent, meaning that higher doses may lead to a greater likelihood of tremors.

In contrast, drugs like co-trimoxazole, mycophenolate mofetil, and prednisolone are less commonly associated with causing tremors. Co-trimoxazole is mainly an antibiotic and does not typically cause neurological side effects related to tremors. Mycophenolate mofetil is also primarily an immunosuppressive agent but does not have a well-documented association with tremors. Prednisolone, a corticosteroid, has numerous side effects but tremors are not considered a